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Words near each other
・ Melanonaclia nigra
・ Melanonaclia perplexa
・ Melanonaclia toulgoeti
・ Melanonus
・ Melanonychia
・ Melanopais gemmaria
・ Melanopella
・ Melanopelta
・ Melanopeziza
・ Melanophagi
・ Melanophidium
・ Melanophidium bilineatum
・ Melanophidium punctatum
・ Melanophidium wynaudense
・ Melanophila
Melanophilin
・ Melanophloea
・ Melanophlogite
・ Melanophryne
・ Melanophryne barbatula
・ Melanophryne carpish
・ Melanophryniscus
・ Melanophryniscus admirabilis
・ Melanophryniscus atroluteus
・ Melanophryniscus cambaraensis
・ Melanophryniscus cupreuscapularis
・ Melanophryniscus devincenzii
・ Melanophryniscus dorsalis
・ Melanophryniscus fulvoguttatus
・ Melanophryniscus klappenbachi


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Melanophilin : ウィキペディア英語版
Melanophilin

Melanophilin is a carrier protein which in humans is encoded by the ''MLPH'' gene. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
== Function ==

This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79083 )
In melanocytic cells MLPH gene expression may be regulated by MITF.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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