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Mesylate
In chemistry, a mesylate is any salt or ester of methanesulfonic acid (CH3SO3H). In salts, the mesylate is present as the CH3SO3− anion. When modifying the International Nonproprietary Name of a pharmaceutical substance containing the group or anion, the correct spelling is mesilate (as in ''imatinib mesilate'', the mesylate salt of imatinib).〔 Retrieved 5 December 2008.〕 Mesylate esters are a group of organic compounds that share a common functional group with the general structure CH3SO2O–R, abbreviated MsO–R, where R is an organic substituent. Mesylate is considered a leaving group in nucleophilic substitution reactions. ==Preparation== Mesylates are generally prepared by treating an alcohol and methanesulfonyl chloride in the presence of a base, such as triethylamine.〔 (a procedure illustrating the use of mesylates).〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Mesylate」の詳細全文を読む
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