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・ Methylaspartate mutase
・ Methylaspartic acid
・ Methylated DNA immunoprecipitation
・ Methylated-DNA—(protein)-cysteine S-methyltransferase
・ Methylated-thiol-coenzyme M methyltransferase
・ Methylation
・ Methylation induced premeiotically
・ Methylation specific oligonucleotide microarray
・ Methylatropine
・ Methylazoxymethanol acetate
・ Methylbenzylpiperazine
・ Methylbutyltryptamine
・ Methylcatechol
・ Methylchloroisothiazolinone
・ Methylcholanthrene
Methylcobalamin
・ Methylcrotonyl-CoA
・ Methylcrotonyl-CoA carboxylase
・ Methylcyclohexane
・ Methylcyclopentadiene
・ Methylcyclopentadienyl manganese tricarbonyl
・ Methylcyclopentane
・ Methylcyclopropane
・ Methyldesorphine
・ Methyldiborane
・ Methyldibromo glutaronitrile
・ Methyldichloroarsine
・ Methyldienolone
・ Methyldihydromorphine
・ Methyldopa


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Methylcobalamin : ウィキペディア英語版
Methylcobalamin

Methylcobalamin (mecobalamin, MeCbl, or MeB) is a cobalamin, a form of . It differs from cyanocobalamin in that the cyanide is replaced by a methyl group. Methylcobalamin features an octahedral cobalt(III) centre. Methylcobalamin can be obtained as bright red crystals.〔 From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal-alkyl bonds. Nickel-methyl intermediates have been proposed for the final step of methanogenesis.
Methylcobalamin is equivalent physiologically to vitamin B, and can be used to prevent or treat pathology arising from a lack of vitamin B (vitamin B12 deficiency), such as pernicious anemia.
Methylcobalamin is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.
==Production==

Methylcobalamin can be produced in the laboratory by reducing cyanocobalamin with sodium borohydride in alkaline solution, followed by the addition of methyl iodide.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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