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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Methylnitronitrosoguanidine ： ウィキペディア英語版 Methylnitronitrosoguanidine |Section2= |Section3= }} Methylnitronitrosoguanidine (MNNG or MNG) is a biochemical tool used experimentally as a carcinogen and mutagen.〔 It acts by adding alkyl groups to the O6 of guanine and O4 of thymine, which can lead to transition mutations between GC and AT. These changes do not cause a heavy distortion in the double helix of DNA and thus are hard to detect by the DNA mismatch repair system. In organic chemistry, MNNG is used as a source of diazomethane when reacted with aqueous potassium hydroxide. MNNG is a probable human carcinogen listed as an IARC Group 2A carcinogen.〔(N-METHYL-N'-NITRO-N-NITROSOGUANIDINE (MNNG) ), International Agency for Research on Cancer〕 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Methylnitronitrosoguanidine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.