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|Section2= |Section6= |Section7= }} Methisazone (USAN) or metisazone (INN) is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses. It has been used in the past to treat smallpox.〔(Methisazone ), Merriam-Webster's Medical Dictionary〕 Methisazone has been described as being used in prophylaxis since at least 1965. ==Synthesis== When isatin is treated with NaH and MeI, the acidic hydrogen is alkylated to product 2. Then, reaction of the ketone carbonyl with thiosemicarbazine (3) leads to methisazone (4). 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Metisazone」の詳細全文を読む スポンサード リンク
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