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Metronidazole : ウィキペディア英語版
Metronidazole


Metronidazole (MNZ), marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication.〔 It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis among others. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.〔 It is the drug of choice for a first episode of mild-to-moderate ''Clostridium difficile'' colitis. Metronidazole is available by mouth, as a cream, and intravenously.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/metronidazole.html )

Common side effects include nausea, a metallic taste, loss of appetite, and headaches. Occasionally seizures or allergies to the medication may occur. Metronidazole should not be used in early pregnancy but appears to be okay in later pregnancy. It should not be used when breastfeeding.〔

Metronidazole began to be commercially used in 1960 in France. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is available in most areas of the world. The pills are not very expensive being between 0.01 and 0.10 USD each. In the United States it is about 26 USD for ten days of treatment.〔
==Medical uses==
Metronidazole is primarily used to treat: bacterial vaginosis, pelvic inflammatory disease (along with other antibacterials like ceftriaxone), pseudomembranous colitis, aspiration pneumonia, rosacea (topical), fungating wounds (topical), intra-abdominal infections, lung abscess, periodontitis, amoebiasis, oral infections, giardiasis, trichomoniasis, and infections caused by susceptible anaerobic organisms such as ''Bacteroides, Fusobacterium, Clostridium, Peptostreptococcus'', and ''Prevotella'' species.〔 It is also often used to eradicate ''Helicobacter pylori'' along with other drugs and to prevent infection in people recovering from surgery.〔 It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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