翻訳と辞書
Words near each other
・ Mir, Iran
・ Mir-1
・ Mir-1 microRNA precursor family
・ Mir-10 microRNA precursor family
・ Mir-101 microRNA precursor family
・ Mir-103/107 microRNA precursor
・ Mir-11 microRNA precursor family
・ MiR-122
・ Mir-124 microRNA precursor family
・ Mir-126
・ Mir-127
・ Mir-129 microRNA precursor family
・ Mir-130 microRNA precursor family
・ MiR-132
・ Mir-133 microRNA precursor family
MiR-134
・ Mir-135 microRNA precursor family
・ Mir-137
・ MiR-138
・ Mir-14 microRNA precursor family
・ Mir-143
・ MiR-144
・ Mir-145
・ MiR-146
・ Mir-148/mir-152 microRNA precursor family
・ Mir-15 microRNA precursor family
・ MiR-150
・ Mir-153 microRNA precursor family
・ Mir-154 microRNA precursor family
・ MiR-155


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MiR-134 : ウィキペディア英語版
MiR-134

miR-134 is a family of microRNA precursors found in mammals, including humans. MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. The excised region or, mature product, of the miR-134 precursor is the microRNA mir-134.
miR-134 was one of a number of microRNAs found to be increasingly expressed in schizophrenia.
==Functions==
miR-134 is a brain-specific microRNA; in rats it is localised specifically in hippocampal neurons and may indirectly regulate synaptic development through antisense pairing with LIMK1 mRNA. In the human brain, SIRT1 is thought to mediate CREB protein through miR-134, giving the microRNA a role in higher brain functions such a memory formation.
miR-134 has also been reported to function in mouse embryonic stem cells as part of a complex network regulating their differentiation.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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