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MiR-150 __NOTOC__ miR-150 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference. miR-150 functions in hematopoiesis; it regulates genes whose downstream products encourage differentiating stem cells towards becoming megakaryocytes rather than erythrocytes. It is also thought to control B and T cell differentiation, alongside mir-155. ==Expression== The expression pattern of miR-150 varies during the differentiation of a hematopoietic stem cell lineage. Highest expression levels occur in mature, resting B and T cells but miR-150 is downregulated in their progenitor cells, including Th1 and Th2 cells.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「MiR-150」の詳細全文を読む
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