翻訳と辞書
Words near each other
・ Mir-133 microRNA precursor family
・ MiR-134
・ Mir-135 microRNA precursor family
・ Mir-137
・ MiR-138
・ Mir-14 microRNA precursor family
・ Mir-143
・ MiR-144
・ Mir-145
・ MiR-146
・ Mir-148/mir-152 microRNA precursor family
・ Mir-15 microRNA precursor family
・ MiR-150
・ Mir-153 microRNA precursor family
・ Mir-154 microRNA precursor family
MiR-155
・ Mir-156 microRNA precursor
・ Mir-16 microRNA precursor family
・ Mir-160 microRNA precursor family
・ Mir-166 microRNA precursor
・ Mir-17 microRNA precursor family
・ Mir-172 microRNA precursor family
・ Mir-181 microRNA precursor
・ Mir-184
・ Mir-185 microRNA precursor family
・ Mir-186 microRNA precursor family
・ Mir-187 microRNA precursor family
・ Mir-188 microRNA precursor family
・ Mir-19 microRNA precursor family
・ Mir-190 microRNA precursor family


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MiR-155 : ウィキペディア英語版
MiR-155

MiR-155 is a microRNA that in humans is encoded by the ''MIR155'' host gene or ''MIR155HG''.〔 MiR-155 plays a role in various physiological and pathological processes. Exogenous molecular control ''in vivo'' of miR-155 expression may inhibit malignant growth, viral infections, and enhance the progression of cardiovascular diseases.
== Discovery ==

The ''MIR155HG'' was initially identified as a gene that was transcriptionally activated by promoter insertion at a common retroviral integration site in B-cell lymphomas and was formerly called BIC (B-cell Integration Cluster). It was later found that the ''MIR155HG'' was composed of three exons that span a 13 kb region within human chromosome 21 (Hsa21 band q21.3) (see Figure 1). The ''MIR155HG'' is transcribed by RNA polymerase II and the resulting ~1,500 nucleotide RNA is capped and polyadenylated. The 23 nucleotide single-stranded miR-155, which is harbored in exon 3, is subsequently processed from the parent RNA molecule.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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