翻訳と辞書 Words near each other ・ Mir-210 microRNA ・ MiR-212 ・ MiR-214 ・ Mir-216 microRNA precursor family ・ Mir-218 microRNA precursor family ・ Mir-219 microRNA precursor family ・ Mir-22 ・ Mir-221 microRNA ・ Mir-223 ・ MiR-224 ・ Mir-23 microRNA precursor family ・ Mir-24 microRNA precursor family ・ Mir-241 microRNA precursor family ・ Mir-25 microRNA precursor family ・ Mir-26 microRNA precursor family ・ MiR-27 ・ Mir-275 microRNA precursor family ・ Mir-277 microRNA precursor family ・ Mir-278 microRNA precursor family ・ Mir-279 microRNA precursor family ・ MiR-27b microRNA precursor ・ Mir-28 microRNA precursor family ・ Mir-281 microRNA precursor family ・ Mir-282 microRNA precursor family ・ Mir-29 microRNA precursor ・ MiR-296 ・ Mir-299 microRNA precursor family ・ Mir-3 microRNA precursor family ・ Mir-30 microRNA precursor ・ Mir-301 microRNA precursor family Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MiR-27 ： ウィキペディア英語版 MiR-27 miR-27 is a family of microRNA precursors found in animals, including humans. MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. The excised region or, mature product, of the miR-27 precursor is the microRNA mir-27. ''Herpesvirus saimiri'' expresses several non-coding RNAs (HSURs) which have been found to significantly reduce the level of mir-27 in a host cell. It has been proposed that miR-27 operates together with miR-23 and mir-24 in a co-operative cluster. ==Regulation of adipocyte differentiation== miR-27 is one of a number of microRNAs implicated in cholesterol homeostasis and fatty acid metabolism. The miR-27 gene family has been shown to be downregulated during the differentiation of adipocytes. miR-27 overexpression inhibits adipocyte formation when overexpressed, acting by blocking the expression of two main regulators of adipogenesis. MicroRNAs miR-27a and -27b have been found to negatively regulate adipocyte differentiation through regulation of the peroxisome proliferator-activated receptor gamma (PPARγ) post-transcriptionally, as well as C/EBP alpha in the case of miR-27b. miR-27 can be identified both as an adipogenic inhibitor and as playing an important role in the development of obesity.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MiR-27」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.