翻訳と辞書
Words near each other
・ Mir-23 microRNA precursor family
・ Mir-24 microRNA precursor family
・ Mir-241 microRNA precursor family
・ Mir-25 microRNA precursor family
・ Mir-26 microRNA precursor family
・ MiR-27
・ Mir-275 microRNA precursor family
・ Mir-277 microRNA precursor family
・ Mir-278 microRNA precursor family
・ Mir-279 microRNA precursor family
・ MiR-27b microRNA precursor
・ Mir-28 microRNA precursor family
・ Mir-281 microRNA precursor family
・ Mir-282 microRNA precursor family
・ Mir-29 microRNA precursor
MiR-296
・ Mir-299 microRNA precursor family
・ Mir-3 microRNA precursor family
・ Mir-30 microRNA precursor
・ Mir-301 microRNA precursor family
・ Mir-305 microRNA precursor family
・ Mir-31
・ Mir-3180 microRNA precursor family
・ Mir-32 microRNA precursor family
・ Mir-320
・ Mir-322 microRNA precursor family
・ Mir-326 microRNA precursor family
・ MiR-33
・ Mir-330 microRNA precursor family
・ Mir-331 microRNA precursor family


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MiR-296 : ウィキペディア英語版
MiR-296
__NOTOC__
miR-296 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference.
miR-296 has been named an "angiomiR" due to being characterised as a microRNA which regulates angiogenesis, the process of growth and creation of new blood vessels.〔 〕 miR-296 is thought to have a specific role in cancer in promoting tumour angiogenesis.〔 It achieves this by targeting HGS mRNA, reducing its expression in endothelial cells which then results in greater number of VEGF receptors.〔
miR-296 has predicted target sites in the transcription factor NANOG and may also contribute to carcinogenesis by dysregulating p53.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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