翻訳と辞書 Words near each other ・ Mir-BHRF1-1 microRNA precursor family ・ Mir-BHRF1-2 microRNA precursor family ・ Mir-BHRF1-3 microRNA precursor family ・ Mir-Fatah-Agha ・ Mir-Hadi Gharaseyyed Romiani ・ Mir-Hossein Mousavi ・ Mir-30 microRNA precursor ・ Mir-301 microRNA precursor family ・ Mir-305 microRNA precursor family ・ Mir-31 ・ Mir-3180 microRNA precursor family ・ Mir-32 microRNA precursor family ・ Mir-320 ・ Mir-322 microRNA precursor family ・ Mir-326 microRNA precursor family ・ MiR-33 ・ Mir-330 microRNA precursor family ・ Mir-331 microRNA precursor family ・ Mir-337 microRNA precursor family ・ MiR-338 ・ Mir-339 microRNA precursor family ・ Mir-34 microRNA precursor family ・ Mir-340 microRNA precursor family ・ Mir-344 microRNA precursor family ・ Mir-345 microRNA precursor family ・ Mir-346 microRNA precursor family ・ Mir-350 microRNA precursor family ・ Mir-351 microRNA precursor family ・ Mir-361 microRNA precursor family ・ Mir-363 microRNA precursor family Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MiR-33 ： ウィキペディア英語版 MiR-33 miR-33 is a family of microRNA precursors, which are processed by the Dicer enzyme to give mature microRNAs. miR-33 is found in several animal species, including humans. In some species there is a single member of this family which gives the mature product mir-33. In humans there are two members of this family called mir-33a and mir-33b, which are located in intronic regions within two protein-coding genes for Sterol regulatory element-binding proteins (SREBP-2 and SREBP-1) respectively. ==Function== miR-33 plays a role in lipid metabolism; it downregulates a number of ABC transporters, including ABCA1 and ABCG1, which in turn regulate cholesterol and HDL generation. Further related roles of miR-33 have been proposed in fatty acid degradation and in macrophage response to low-density lipoprotein.〔 It has been suggested that miR-33a and miR-33b regulates genes Involved in fatty acid metabolism and insulin signalling. Potential binding sites for mir-33 have been identified in the cDNA of tumour suppressor p53. Further, study has shown that miR-33 is able to repress p53 expression and p53-induced apoptosis. This function is thought to be related to hematopoietic stem cell renewal. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MiR-33」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.