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Midol is a brand of an over-the-counter drug for menstrual cramping and other effects related to premenstrual syndrome and menstruation. Midol is distributed by Bayer. Midol was originally sold in 1911 as a headache and toothache remedy that was considered safer because it did not use the narcotics typically used at the time.〔(Midol ad for Headache--Neuralgia, Toothache )〕 It was then promoted as a cure for hiccups claiming it controlled spasms, and finally as a remedy for menstrual cramps and bloating.〔(Midol for Hiccoughs )〕〔(News at Museum of Menstruation and women's health )〕〔(Midol ad for Menstrual problems )〕〔( Midol "Reverse the Curse" ad )〕 A formulation sold in the 1980s was made with the sympathomimetic cinnamedrine.〔KW Fellows, AJ Giannini. Cinnamedrine: Potential for Abuse. Journal of Toxicology:Clinical Toxicology. 20:93–99.1983.〕 It had been reported to have abuse potential as an appetite suppressant and sympathomimetic agent. The "Midol Complete" formulation consists of: * Acetaminophen 500 mg (pain reliever) * Caffeine 60 mg (stimulant) * Pyrilamine maleate 15 mg (antihistamine) The "Extended Relief" formulation consists of: * Naproxen sodium 220 mg (NSAID, pain reliever/fever reducer) The "Teen" formulation consists of: * Acetaminophen 500 mg (pain reliever) * Pamabrom 25 mg (diuretic) The "Liquid Gels" formulation consists of: * Ibuprofen 200 mg (pain reliever) The "PM" formulation consists of: * Acetaminophen 500 mg (pain reliever) * Diphenhydramine citrate 38 mg (sedative antihistamine) ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Midol」の詳細全文を読む スポンサード リンク
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