翻訳と辞書
Words near each other
・ Mir Yusof
・ Mir Yusof-e Olya
・ Mir Yusof-e Sofla
・ Mir Zafar Ali
・ Mir, Belarus
・ Mir, Iran
・ Mir-1
・ Mir-1 microRNA precursor family
・ Mir-10 microRNA precursor family
・ Mir-101 microRNA precursor family
・ Mir-103/107 microRNA precursor
・ Mir-11 microRNA precursor family
・ MiR-122
・ Mir-124 microRNA precursor family
・ Mir-126
Mir-127
・ Mir-129 microRNA precursor family
・ Mir-130 microRNA precursor family
・ MiR-132
・ Mir-133 microRNA precursor family
・ MiR-134
・ Mir-135 microRNA precursor family
・ Mir-137
・ MiR-138
・ Mir-14 microRNA precursor family
・ Mir-143
・ MiR-144
・ Mir-145
・ MiR-146
・ Mir-148/mir-152 microRNA precursor family


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Mir-127 : ウィキペディア英語版
Mir-127

mir-127 microRNA is a short non-coding RNA molecule with interesting overlapping gene structure. miR-127 functions to regulate the expression levels of genes involved in lung development, placental formation and apoptosis. Aberrant expression of miR-127 has been linked to different cancers.
==Gene structure==

pri-miR-127 is derived from a separate but overlapping conserved gene cluster coding for miR-433/127. miR-127 and miR-433 are overlapped in a 5’-3’ direction. Although the loci could be found on different chromosomes in different species, the structure has been conserved. In mammals including human, chimpanzee, horse, dog, monkey, rat, cow, and mouse, multiple sequence alignments (MSA) between miR-433 and miR127 have shown 95-100% similarity with a conserved distance between miR-433 and miR-127 of 986 to 1007 bp. Moreover, the upstream response elements in the miR-433/127 promoters, including estrogen related receptors response element (ERRE) have been conserved among above species. Data have suggested that that miR-433/127 loci may have evolved from a common gene of origin.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Mir-127」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.