翻訳と辞書
Words near each other
・ Mir-58 microRNA precursor family
・ Mir-580 microRNA precursor family
・ Mir-584 microRNA precursor family
・ Mir-589 microRNA precursor family
・ Mir-590 microRNA precursor family
・ Mir-592 microRNA precursor family
・ Mir-598 microRNA precursor family
・ Mir-6 microRNA precursor
・ Mir-601 microRNA precursor family
・ Mir-605 microRNA precursor family
・ Mir-61 microRNA precursor family
・ Mir-612 microRNA precursor family
・ Mir-615 microRNA precursor family
・ Mir-616 microRNA precursor family
・ Mir-181 microRNA precursor
Mir-184
・ Mir-185 microRNA precursor family
・ Mir-186 microRNA precursor family
・ Mir-187 microRNA precursor family
・ Mir-188 microRNA precursor family
・ Mir-19 microRNA precursor family
・ Mir-190 microRNA precursor family
・ MiR-191
・ Mir-192/215 microRNA precursor
・ Mir-193 microRNA precursor family
・ Mir-194 microRNA precursor family
・ Mir-196 microRNA precursor family
・ Mir-198 microRNA precursor family
・ Mir-199 microRNA precursor
・ Mir-2


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Mir-184 : ウィキペディア英語版
Mir-184

In molecular biology, miR-184 microRNA is a short non-coding RNA molecule. MicroRNAs (miRNAs) function as posttranscriptional regulators of expression levels of other genes by several mechanisms. Several targets for miR-184 have been described, including that of mediators of neurological development, apoptosis and it has been suggested that miR-184 plays an essential role in development.
MicroRNAs can bind to the three prime untranslated region (3’UTR) of the target messenger RNA (mRNA). Binding of the miRNA can hinder translation of mRNA by promoting degradation or inducing deadenylation.
==Genomic location==
miR-184 is a single copy gene and evolutionarily conserved at the nucleotide level from flies to humans. In humans, miR-184 is located within region 25.1 on the q-arm of chromosome 15, and its corresponding transcript is comparatively small (84bp) which is not encoded near other clustered miRNAs. In the mouse genome, miR-184 is located in an imprinted locus on mouse chromosome 9, and it is 55 kb away from the nearest coding gene.
The genomic region immediately surrounding miR-184 does not contain a classic CpG island, but does contain several CpG-rich sequences that are suitable for MBD1 binding.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Mir-184」の詳細全文を読む



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