| 翻訳と辞書 |
MitraClip
MitraClip is a novel, percutaneous method of treatment that is targeted for patients who have been denied surgery to fix mitral valve regurgitation.〔Wan, B., Rahnavardi, M., Tian, D.H., Phan, K., Munkholm-Larsen, S., Bannon, P.G., Yan, T.D. (2013). A meta-analysis of MitraClip system versus surgery for treatment to severe mitral regurgitation. Ann Cardiothorac Surg, 2, 683-692.〕 MitraClip is the only alternative to mitral valve regurgitation surgery that has been approved by the FDA.〔Sundermann, S.H., Biaggi, P., Grunenfelder, J., Gessat, M., Felix, C., Bettex, D., Falk, V., Corti, R. (2014). Safety and feasibility of novel technology fusing echocardiography and fluoroscopy images during MitraClip interventions. EuroInterventions, 9, 1210-1216.〕 Open-heart surgery is the standard method of treatment for patients with mitral valve regurgitation, however it is very invasive and not a feasible option for all patients.〔Perl, L., Vaturi, M., Assali, A., Shapira, Y., Bruckheimer, E., Ben-Gal, T., Vaknin-Assa, h., Sagie, A., Kornowski, R. (2013). Preliminary Experience Using the Transcatheter Mitral Valve Leaflet Repair Procedure. Israel Med Assoc J, 15, 608-612.〕 The risk of complications and mortality greatly increase in patients with other health conditions like liver disease, previous chest surgeries, and age above 75, which is why they are often denied surgery.〔Whitlow, P.L., Feldman, T., Pedersen, W.R., Lim, D.S., Kipperman, R., Smalling, R., Bajwa, T., Herrmann, H.C., Lasala, J., Maddux, J.T., Tuzcu, M., Kapadia, S., Trento, A., Siegel, R.J., Foster, E., Glower, D., Mauri, L., Kar, S. (2012). Acute and 12-Month Results With Catheter-Based Mitral Valve Leaflet Repair. J Am Coll Cardiol, 59, 130-139.〕 The implantation of MitraClip does not involve open-heart surgery, but mimics the surgical method of edge-to-edge valve repair.〔 The mitral valve leaflets are clipped together with the device instead of being sutured together, making this procedure much less invasive but still effective.〔Feldman, T., Kar, S., Rinaldi, M., Fail, P., Hermiller, J., Whitlow P.L., Gray, W., Low, R., Herrmann, H.C., Lim, S., Foster, E., Glower, D. (2009). Percutaneous Mitral Repair With the MitraClip System. J Am Coll Cardiol, 54, 686-694.〕 The MitraClip is made of chromium and cobalt and is covered in polyester to promote the growth of tissue around the clip.〔
MitraClip is manufactured by Abbott Laboratories.
==Procedure==
Patients are placed under a general anesthetic and a catheter, containing the MitraClip is inserted into the femoral vein.〔 Fluoroscopy helps the surgeon to guide the device through the venous system to the heart. Once at the heart, echocardiography is used to position the device at the mitral valve.〔 The device enters the heart through the inferior vena cava to the right atrium. The surgeon will pass the catheter through the septal wall between the two atria, allowing the device to pass to the left atrium.〔 This is a very precise puncture that requires both the echocardiography and fluoroscopy images to locate the proper area. The MitraClip is opened and passes through the annulus into the left ventricle and sits below the leaflets.〔 Once on the ventricular side of the mitral valve, the MitraClip is opened and pulled towards the atria. The open MitraClip grabs both mitral valve leaflets, the surgeon closes the clip, and the leaflets are clipped together.〔 Fastening the clip to the leaflets decreases regurgitant blood.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「MitraClip」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|