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Mitraphylline : ウィキペディア英語版 | Mitraphylline
|Section2= }} Mitraphylline, an oxindole derivative, is an active alkaloid in the leaves of the tree ''Mitragyna speciosa'', commonly known as kratom. As a non-narcotic constituent, it also occurs to a significant amount in the bark of ''Uncaria tomentosa'' (Cat’s Claw) along with a number of isomeric alkaloids. Due to its structural similarity to mitragynine and 7-hydroxymitragynine from kratom, effects on mu and delta opiate receptors as well as NMDA-antagonistic actions have been postulated. Current research is focussing on antiproliferative and cytotoxic effects and its ''in vivo'' efficacy to induce apoptosis in human breast cancer, sarcoma as well as lymphoblastic leukaemia cell lines. == References ==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Mitraphylline」の詳細全文を読む
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