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Mosapramine
Mosapramine (Cremin) is an atypical antipsychotic used in Japan.〔Takahashi N, Terao T, Oga T, Okada M. Comparison of risperidone and mosapramine addition to neuroleptic treatment in chronic schizophrenia. ''Neuropsychobiology''. 1999;39(2):81-5. PMID 10072664〕 It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors,〔Futamura T, Ohashi Y, Yano K, Takahashi Y, Haga K, Fukuda T. The affinities of mosapramine for the dopamine receptor subtypes in human cell lines expressing D2, D3 and D4 receptors. ''Nippon Yakurigaku Zasshi''. (Japanese) 1996 May;107(5):247-53. PMID 8690306〕 and with moderate affinity for the 5-HT2 receptors.〔Sumiyoshi T, Suzuki K, Sakamoto H, Yamaguchi N, Mori H, Shiba K, Yokogawa K. Atypicality of several antipsychotics on the basis of in vivo dopamine-D2 and serotonin-5HT2 receptor occupancy. ''Neuropsychopharmacology''. 1995 Feb;12(1):57-64. PMID 7766287〕 == See also ==
* Carpipramine * Clocapramine
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Mosapramine」の詳細全文を読む
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