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Musashi2
The first Musashi (abbreviation Msi) gene was firstly found in the flies’ family Drosophila, although it has been later identified in other eukaryotic species. There are two homologue genes found in mammals, called Musashi 1 (MSI1) and Musashi 2 (Msi2). The last one is expressed as a RNA-binding protein in neuronal progenitor cells, including stem cells, and both normal and leukemic blood cells.〔Andrés-Aguayo L, Varas F, Graf T. ''Musashi 2 in hematopoiesis''. Curr Opin Hematol. 2012 Jul; 19(4); 268-72. http://www.ncbi.nlm.nih.gov/pubmed/22517588〕〔Michael G Kharas, Christopher J Lengner, Fatima Al-Shahrour, Lars Bullinger, Brian Ball, Samir Zaidi, Kelly Morgan, Winnie Tam, Mahnaz Paktinat, Rachel Okabe,Maricel Gozo, William Einhorn, Steven W Lane, Claudia Scholl, Stefan Fröhling, Mark Fleming, Benjamin L Ebert, D Gary Gilliland, Rudolf Jaenisch and George Q Daley. ''Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia''. Nat Med. 2010 Aug ; 16(8): 903–908. doi:10.1038/nm.2187. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090658/pdf/nihms283893.pdf〕 == Location ==
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