翻訳と辞書 Words near each other ・ N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase ・ N,N'-diacetylchitobiose phosphorylase ・ N,N'-diacetyllegionaminate synthase ・ N,N'-Dicyclohexylcarbodiimide ・ N,N'-Diisopropylcarbodiimide ・ N,N'-Methylenebisacrylamide ・ N,N-Diisopropylaminoethanol ・ N,N-Diisopropylethylamine ・ N,N-Dimethyl-1-naphthylamine ・ N,N-Dimethyldopamine ・ N,N-Dimethylethylamine ・ N,N-dimethylformamidase ・ N,N-Dimethylsphingosine ・ N,N-Dimethyltryptamine ・ N,N′-Dimethyl-1,3-propanediamine ・ N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate ・ N,O-Dimethylhydroxylamine ・ N- ・ N-(1-Naphthyl)ethylenediamine ・ N-(2-Hydroxypropyl) methacrylamide ・ N-(long-chain-acyl)ethanolamine deacylase ・ N-(p-amylcinnamoyl)anthranilic acid ・ N-(S)-Fenchyl-1-(2-morpholinoethyl)-7-methoxyindole-3-carboxamide ・ N-105 National Highway ・ N-110 National Highway ・ N-110 road (Spain) ・ N-111 road (Spain) ・ N-113 road (Spain) ・ N-120 National Highway ・ N-120 road (Spain) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate ： ウィキペディア英語版 N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate ''N'',''O''-Dimethyl-4β-(2-naphthyl)piperidine-3β-carboxylate (DMNPC) is a piperidine based stimulant drug which is synthesised from arecoline. It is similar to nocaine in chemical structure, and has two and a half times more activity than cocaine as a dopamine reuptake inhibitor. However it is also a potent serotonin reuptake inhibitor, with similar affinity to fluoxetine.〔(【引用サイトリンク】title=Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. Potent Dopamine and Serotonin Reuptake Inhibitors )〕 It is a structural isomer of another potent dopamine reuptake inhibitor, HDMP-28. Clearly it is not just the SS enantiomer of the title compound that is an active MAT inhibitor. ==Effect of ''N''-demethylation== Interestingly, for the SR enantiomer, increased DAT affinity is seen upon demethylation. This is the same choice of isomer used in the production of Paxil. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.