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N-Acetylglutamate : ウィキペディア英語版
N-Acetylglutamic acid

| CASNo = 5817-08-3
| CASNo_Ref =
| CASNo1 = 19146-55-5
| CASNo1_Ref =
| CASNo1_Comment = ''R''
| CASNo2 = 1188-37-0
| CASNo2_Ref =
| CASNo2_Comment = ''S''
| PubChem = 185
| PubChem1 = 1560015
| PubChem1_Comment = ''R''
| PubChem2 = 70914
| PubChem2_Comment = ''S''
| ChemSpiderID = 180
| ChemSpiderID_Ref =
| ChemSpiderID1 = 1272049
| ChemSpiderID1_Ref =
| ChemSpiderID1_Comment = ''R''
| ChemSpiderID2 = 64077
| ChemSpiderID2_Comment = ''S''
| ChemSpiderID2_Ref =
| EINECS = 227-388-6
| DrugBank = DB04075
| DrugBank_Ref =
| KEGG = C00624
| KEGG_Ref =
| MeSHName = N-acetylglutamate
| ChEBI = 17533
| ChEBI_Ref =
| RTECS = LZ9725000 ''S''
| Beilstein = 1727473 ''S''
| 3DMet = B00147
| SMILES = Cc(:()):()C(CCc(:()):())c(()):()
| SMILES1 = CC(=O)NC(CCC(O)=O)C(O)=O
| StdInChI = 1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)
| StdInChI_Ref =
| StdInChIKey = RFMMMVDNIPUKGG-UHFFFAOYSA-N
| StdInChIKey_Ref =
| InChI1 = 1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t5-/m1/s1
| InChIKey1 = RFMMMVDNIPUKGG-RXMQYKEDSA-N
| InChI2 = 1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t5-/m0/s1
| InChIKey2 = RFMMMVDNIPUKGG-YFKPBYRVSA-N
}}
|Section2=
|Section3=
|Section4=
}}
''N''-Acetylglutamic acid (abbreviated NAcGlu) is biosynthesized from glutamic acid and acetyl-CoA by the enzyme ''N''-acetylglutamate synthase. Arginine is the activator for this reaction.
The reverse reaction, hydrolysis of the acetyl group, is catalyzed by a specific hydrolase.
NAcGlu activates carbamoyl phosphate synthetase in the urea cycle.
==See also==

* Glutamate
* Glutamic acid

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「N-Acetylglutamic acid」の詳細全文を読む



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