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N-Methylconiine : ウィキペディア英語版 | N-Methylconiine
''N''-Methylconiine is a poisonous alkaloid found in poison hemlock in small quantities. == Isolation and properties == The D-(+)-stereoisomer of ''N''-methylconiine is reported to occur in hemlock in small quantities,〔Planta and Kekulé, ''Annalen,'' 1854, 89, 150.〕 and methods for its isolation are described by Wolffenstein〔''Ber.,'' 1894, 27, 2615; 1895, 28, 302〕 and by von Braun.〔''Ber.,'' 1905, 38, 3108; 1917, 50, 1477.〕 It is a colourless, oily, coniine-like liquid, specific rotation ()D +81.33° at 24.3 °C. The salts are crystalline ("B" marks one molecule of the base): the hydrochloride, B•HCl, forms masses of needles, mp. 188 °C; the platinichloride, B2•H2PtCl6, has mp. 158 °C. The L-(−)-stereoisomer was obtained by Ahrens〔''Ber.,'' 1902, 35, 1330; ''cf.'' Löffler and Friedrich, ''ibid.,'' 1909, 42, 107.〕 from residues left in the isolation of coniine as hydrobromide or by removing coniine as the nitroso-compound. It is a colourless, coniine-like liquid, bp. 175.6 °C/767 mmHg, specific rotation ()D −81.92° at 20 °C. The monohydrochloride crystallises in leaflets, mp. 191–192 °C; the monohydrobromide in leaflets, mp. 189–190 °C; the platinichloride in orange crystals, mp. 153–154 °C; the aurichloride in leaflets, mp. 77–78 °C; and the picrate in long needles, mp. 121–122 °C.
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