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・ N-myc-interactor
・ N-myristoyltransferase 1
・ N-Nitroso-N-methylurea
・ N-Nitrosodimethylamine
・ N-Nitrosonornicotine
・ N-nucleotide
・ N-Octyl beta-D-thioglucopyranoside
・ N-Octyl bicycloheptene dicarboximide
・ N-ost
・ N-Oxalylglycine
・ N-Oxoammonium salt
・ N-Peace Awards
・ N-Phenethyl-14-ethoxymetopon
・ N-Phenethyl-4-piperidinone
・ N-Phenethylnordesomorphine
N-Phenethylnormorphine
・ N-Phenylnaphthalen-1-amine
・ N-philes
・ N-Plants
・ N-player game
・ N-Prize
・ N-Propyl azide
・ N-Propyl chloride
・ N-Propyl iodide
・ N-Propyl-L-arginine
・ N-Reactor
・ N-red crown (n hieroglyph)
・ N-rule (Icelandic language)
・ N-SAT-110
・ N-Secure


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N-Phenethylnormorphine : ウィキペディア英語版
N-Phenethylnormorphine

''N''-Phenethylnormorphine is an opioid analgesic drug derived from morphine by replacing the ''N''-methyl group with β-phenethyl. It is around eight to fourteen times more potent than morphine as a result of this modification, in contrast to most other N-substituted derivatives of morphine, which are substantially less active, or act as antagonists. Binding studies have helped to explain the increased potency of N-phenethylnormorphine, showing that the phenethyl group extends out to reach an additional binding point deeper inside the mu opioid receptor cleft, analogous to the binding of the phenethyl group on fentanyl.
==See also==

* 14-Cinnamoyloxycodeinone
* 14-Phenylpropoxymetopon
* 7-PET
* MR-2096
* ''N''-Phenethyl-14-ethoxymetopon
* ''N''-Phenethylnordesomorphine
* Phenomorphan
* RAM-378
* Ro4-1539

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「N-Phenethylnormorphine」の詳細全文を読む



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