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NBD-TMA ((HREF="http://www.kotoba.ne.jp/word/11/nitro compound" TITLE="nitro compound">nitro-2,1,3-benzoxadiazol-7-yl)aminoethyl )trimethylammonium) is a small, positively charged (+1) fluorescent dye. It was also known as EAM-1 (N,N,N,-Trimethyl-2()ethanaminium iodide) when it was briefly supplied by Macrocyclics Company as an iodide complex. NBD-TMA has an excitation maximum at 458 nm and an emission maximum at 530 nm. It also has a smaller local excitation maximum around 343 nm. The molar extinction coefficient is about 13,000 cm−1M−1 and its overall effective fluorescence is about 1% that of fluorescein. It is only mildly sensitive to halide ion collision quenching. NBD-TMA was designed as a probe for monitoring renal transport of organic cations. As a small, positively charged fluorophore, it has also seen use as a tracer for measuring gap junction coupling in cases of cation selective connexin channels. == Further reading == * PMID 10864014 * PMID 15869481 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「NBD-TMA」の詳細全文を読む スポンサード リンク
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