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Words near each other
・ Ndubuisi Okosieme
・ Ndudi Ebi
・ Nduduzo Makhathini
・ Ndue Marashi
・ Ndue Paluca
・ Ndue Përlleshi
・ Ndue Ukaj
・ Nduese Essien
・ NDUFA10
・ NDUFA11
・ NDUFA12
・ NDUFA13
・ NDUFA2
・ NDUFA3
・ NDUFA4
NDUFA4L2
・ NDUFA5
・ NDUFA6
・ NDUFA7
・ NDUFA8
・ NDUFA9
・ NDUFAB1
・ NDUFAF1
・ NDUFB1
・ NDUFB10
・ NDUFB11
・ NDUFB2
・ NDUFB3
・ NDUFB4
・ NDUFB5


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NDUFA4L2 : ウィキペディア英語版
NDUFA4L2

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 is a protein that in humans is encoded by the NDUFA4L2 gene. The NDUFA4L2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.
==Structure==
The NDUFA4L2 gene is located on the long q arm of chromosome 12 at position 13.3 and it spans 5,860 base pairs.〔 NDUFA4L2 is a subunit of the enzyme NADH dehydrogenase (ubiquinone), the largest of the respiratory complexes. The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known redox centers and the NADH binding site.〔 It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of Complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and that the hydrophobic domain acts as an anchor for the NADH dehydrogenase (ubiquinone) complex at the inner mitochondrial membrane.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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