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NR5A1 : ウィキペディア英語版
Steroidogenic factor 1

The steroidogenic factor 1 (SF1) protein controls sexual development in the embryo and at puberty.
SF1 is a member of the nuclear receptor family of intracellular transcription factors and is encoded by the ''NR5A1'' gene (nuclear receptor subfamily 5, group A, member 1).
== Function ==

SF-1 is a critical regulator of reproduction, regulating the transcription of key genes involved in sexual development and reproduction, most notably StAR and P450SCC. It can form a transcriptional complex with TDF to up-regulate transcription of the Sox9 gene. Its targets include genes at every level of the hypothalamic-pituitary-gonadal axis, as well as many genes involved in gonadal and adrenal steroidogenesis.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Steroidogenic factor 1」の詳細全文を読む



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