翻訳と辞書 Words near each other ・ NS Puppis ・ NS Railinfratrust ・ NS Savannah ・ NS SGMm ・ NS Sprinter Lighttrain ・ NS Stations ・ NS Timetable 2010 ・ NS VIRM ・ NS Wanderers RC ・ NS Yoon-G ・ NS-11394 ・ NS-2 (character) ・ NS-2000 ・ NS-2359 ・ NS-2664 ・ NS-2710 ・ NS-398 ・ NS-5 Robot (i, Robot movie) ・ NS-Dokumentationszentrum ・ NS-Dokumentationszentrum (Munich) ・ NS-Frauen-Warte ・ NS-Ordensburgen ・ NS-Shaft ・ NS-Tower ・ NS/EP telecommunications ・ NS/Stick ・ NS0 cell ・ NS1 antigen test ・ NS1 influenza protein ・ NS102 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク NS-2710 ： ウィキペディア英語版 NS-2710 NS-2710 (LS-193,970) is an anxiolytic drug with a novel chemical structure, developed by the small pharmaceutical company Neurosearch. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. NS-2710 is a potent but non-selective partial agonist at GABAA receptors, although with little efficacy at the α1 subtype and more at α2 and α3. It has anxiolytic effects comparable to chlordiazepoxide,〔Evenden J, Duncan B, Ko T. A comparison of the effects of psychotomimetics and anxiolytics on punished and unpunished responding maintained by fixed interval schedules of food reinforcement in the rat. ''Behavioural Pharmacology''. 2006 Feb;17(1):87-99. PMID 16377966〕 and while it is a less potent anticonvulsant than the related drug NS-2664, it has a much longer duration of action, and similarly to other α2/α3-preferring partial agonists produces little sedative effects or physical dependence.〔Mirza NR, Nielsen EØ. Do subtype-selective gamma-aminobutyric acid A receptor modulators have a reduced propensity to induce physical dependence in mice? ''Journal of Pharmacology and Experimental Therapeutics''. 2006 Mar;316(3):1378-85. PMID 16352707〕 == References == 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「NS-2710」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.