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NSUN2
NOP2/Sun domain family, member 2 is a protein that in humans is encoded by the ''NSUN2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/54888 )〕 Alternatively spliced transcript variants encoding different isoforms have been noted for the gene. == Function ==
The protein is a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA (Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「NSUN2」の詳細全文を読む
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