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Nucleobindin-1 (NUCB1), also known as calnuc, is a protein that in humans is encoded by the ''NUCB1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4924 )〕 == Structure == The human calnuc protein contains 461 amino acids and has a pI of 4.9. The protein contains the following regions and domains: * Signal peptide * Leucine-zipper〔 The leucine-zipper of calnuc may be responsible for its dimerization. * aa 347-389 – Nuclear localization signal * 2 zinc binding sites with high affinity (Kd = 20 nM) * carboxypeptidase-like motifs : HFREXnH (aa 66) and HFTEXnH (aa 146) * 2 EF-hands * Potential anchor region〔– 15-aa hydrophobic region at its COOH terminus that may be sufficient for membrane anchoring 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「NUCB1」の詳細全文を読む スポンサード リンク
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