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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Nbs1 ： ウィキペディア英語版 Nibrin Nibrin, also known as NBN or Nbs1, is a protein which in humans is encoded by the ''NBN'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4683 )〕 == Function == Nibrin is a protein associated with the repair of double strand breaks (DSBs) which pose serious damage to a genome. It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50(N/M/R, more commonly referred to as MRN) double strand DNA break repair complex.〔(【引用サイトリンク】title=Atlas of Genetics and Cytogenetics in Oncology and Haematology - NBS1 )〕 This complex recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci. It also has a role in regulation of N/M/R (MRN) protein complex activity which includes end-processing of both physiological and mutagenic DNA double strand breaks (DSBs).〔(【引用サイトリンク】title=eMedicine - Nijmegen Breakage Syndrome )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nibrin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.