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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク NeuN ： ウィキペディア英語版 NeuN NeuN (Feminizing Locus on X-3, Fox-3, Rbfox3, or Hexaribonucleotide Binding Protein-3), a homologue to sex-determining genes in ''Caenorhabditis elegans'', is a neuronal nuclear antigen that is commonly used as a biomarker for neurons. ==History== NeuN was first described in 1992 by Mullen et al., who raised a series of monoclonal antibodies to mouse antigens with the original intent of finding mouse species specific immunological markers for use in transplantation experiments. In the event they isolated a hybridoma line, called mAb A60, which proved to bind an antigen expressed only in neuronal nuclei and to a lesser extent the cytoplasm of neuronal cells, and which appeared to work on all vertebrates. This unknown antigen was therefore known as NeuN for "Neuronal Nuclei". In 2009, Kim et al. used proteomic methods to show that NeuN corresponds to a protein known as Rbfox3. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「NeuN」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.