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Neuromelanin : ウィキペディア英語版
Neuromelanin

Neuromelanin (NM) is a dark pigment found in the brain which is structurally related to melanin. It is a polymer of 5,6-dihydroxyindole monomers. Neuromelanin is expressed in large quantities in catecholaminergic cells of the substantia nigra pars compacta and locus coeruleus, giving dark color to the structures.
==Importance in humans==
Neuromelanin is found in higher concentrations among humans than in other primates.〔 Neuromelanin-containing neurons in the substantia nigra undergo neurodegeneration during Parkinson's disease. Neuromelanin concentration increases with age, suggesting a role in neuroprotection (neuromelanin can chelate metals and xenobiotics+) or senescence.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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