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・ Nif gene
・ Nif regulon
・ NIF3L1
・ NIFA
・ Nifa and Nishan Hindes
・ Nifas Silk-Lafto
・ NIFC
・ NiFe Hydrogenase
・ Nifedipine
・ Nifekalant
・ Nifelheim
・ Nifelheim (album)
・ Nifelvind
・ Nifenalol
・ Nifenazone
Nifene
・ Niffer
・ Nifiloli
・ NIFL Championship 1
・ NIFL Championship 2
・ NIFL Charity Shield
・ NIFL Premiership
・ NIFL Reserve League
・ Niflheim
・ Niflhel
・ Niflumic acid
・ NIFOC
・ Niforeika
・ Nifoxipam
・ Niftawayh


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Nifene : ウィキペディア英語版
Nifene

Nifene is a high affinity, selective nicotinic α4β2 receptor agonist used in medical research for nicotinic acetylcholine receptors, usually in the form of nifene (18F) as a positron emission tomography (PET) radiotracer.
Nifene has been used to assess the efficacy of acetylcholinesterase inhibitors in animal models, because the neurotransmitter acetylcholine competes with the binding of nifene at the nicotinic receptor site. Learning and behavior studies in animal models using nifene have suggested a potential role of the nicotinic receptors located in distinct white matter tracts. Nifene studies in animal models of lung cancer have suggested an upregulation of the nicotinic receptor in the lung tumors.〔
〕 Novel PET and SPECT imaging agents as potential receptor antagonists have been developed based on the structure of nifene; niodene for SPECT, nifrolene for PET and niofene for PET/SPECT. These new derivatives take advantage of the unique in vivo imaging properties of nifene.
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Nifene」の詳細全文を読む



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