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Nitrosourea
|Section2= }} Nitrosourea is both the name of a molecule, and a class of compounds that include a nitroso (R-NO) group and a urea. ==Examples== Examples include: * Carmustine * Lomustine * Semustine * Ethylnitrosourea (ENU) * Streptozocin Nitrosourea compounds are DNA alkylating agents and are often used in chemotherapy. They are lipophilic and thus can cross the blood–brain barrier, making them useful in the treatment of brain tumors such as glioblastoma multiforme.〔Takimoto CH, Calvo E. ("Principles of oncologic pharmacotherapy". ) in Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (Eds) (Cancer management: a multidisciplinary approach ). 11 ed. 2008.〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Nitrosourea」の詳細全文を読む
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