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''Nodaviridae'' is a family of viruses. Vertebrates and invertebrates serve as natural hosts. There are currently nine species in this family, divided among 2 genera. Diseases associated with this family include: viral encephalopathy and retinopathy in fishes.〔(【引用サイトリンク】url=http://viralzone.expasy.org/all_by_species/47.html )〕〔(【引用サイトリンク】title=Virus Taxonomy: 2014 Release )〕 ==Virology== The virus is not enveloped and has an icosahedral capsid (triangulation number=3) ranging from 29 to 35 nm in diameter. The capsid is constructed of 32 capsomers.〔〔 The genome is linear, positive sense, bipartite (composed of two segments—RNA1 and RNA2) single stranded RNA consisting of 4500 nucleotides with a 5’ terminal methylated cap and a non-polyadenylated 3’ terminal.〔〔 RNA1, which is ~3.1 kilobases in length, translates encodes a protein that has multiple functional domains: a mitochondrial targeting domain, a transmembrane domain, an RNA-dependent RNA polymerase (RdRp) domain, a self-interaction domain and an RNA capping domain. In addition, RNA1 encodes a subgenomic RNA3 that translates protein B2, an RNA silencing inhibitor.〔〔 RNA2 encodes protein α, a viral capsid protein precursor, which is auto-cleaved into two mature proteins, a 38 kDa β protein and a 5 kDa γ protein, at a conserved Asn/Ala site during virus assembly.〔〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nodaviridae」の詳細全文を読む スポンサード リンク
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