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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Nonabine ： ウィキペディア英語版 Nonabine Nonabine (BRL-4664) is a drug which is a cannabinoid derivative, which was developed for the prevention of nausea and vomiting associated with cancer chemotherapy.〔Staquet M, Bron D, Rozencweig M, Kenis Y. Clinical studies with a THC analog (BRL-4664) in the prevention of cisplatin-induced vomiting. ''Journal of Clinical Pharmacology''. 1981 Aug-Sep;21(8-9 Suppl):60S-63S. PMID 7197692〕 It has strong antiemetic effects equivalent to those of chlorpromazine, and also produces some mild sedative effects, along with dry mouth and EEG changes typical of cannabinoid agonists, but with minimal changes in mood or perception, suggesting the abuse potential is likely to be low.〔Archer CB, Amlot PL, Trounce JR. Antiemetic effect of nonabine in cancer chemotherapy: a double blind study comparing nonabine and chlorpromazine. ''British Medical Journal (Clinical Research Edition)''. 1983 Jan 29;286(6362):350-1. PMID 6402096〕〔McClelland GR, Sutton JA. Pilot investigation of the quantitative EEG and clinical effects of ketazolam and the novel antiemetic nonabine in normal subjects. ''Psychopharmacology (Berlin)''. 1985;85(3):306-8. PMID 2860687〕 == References == 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nonabine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.