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Norrin
Norrin, also known as Norrie disease protein or X-linked exudative vitreoretinopathy 2 protein (EVR2) is a protein that in humans is encoded by the ''NDP'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4693 )〕 Mutations in the NDP gene are associated with the Norrie disease. == Function ==
Signaling induced by the protein Norrin regulates vascular development of vertebrate retina and controls important blood vessels in the ear.〔 Norrin binds with high affinity to Frizzled 4, and Frizzled 4 knockout mice exhibit abnormal vascular development of the retina.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Norrin」の詳細全文を読む
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