翻訳と辞書 ・ O, more, more! ・ O, My Darling Clementine ・ O, O, O... ・ O, Sport, You – the Peace! ・ O, The Oprah Magazine ・ O, Vrba ・ O, Yeah! Ultimate Aerosmith Hits ・ O-1 (airship) ・ O-1057 ・ O-1125 ・ O-1238 ・ O-1269 ・ O-14 (Dubai) ・ O-1602 ・ O-1812 ・ O-1871 ・ O-1918 ・ O-2050 ・ O-2113 ・ O-2172 ・ O-2372 ・ O-2545 ・ O-2694 ・ O-4310 ・ O-6-methylguanine-DNA methyltransferase ・ O-774 ・ O-806 ・ O-823 ・ O-acetylhomoserine aminocarboxypropyltransferase ・ O-Acetylpsilocin
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O-1871
O-1871 is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan in 2002. It has a CB1 receptor affinity of 2.0nM and a CB2 receptor affinity of 0.3nM.〔(Billy R Martin, Raj K Razdan. CANNABINOIDS. Patent WO 2003/091189 )〕 Structurally, O-1871 is a cyclohexylphenol derivative related to CP 47,497, and so is illegal in most jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative,〔(Xin-Zhong Lai, Dai Lu, Alexandros Makriyannis. Novel biphenyl and biphenyl-like cannabinoids. Patent US 2004/0087590 )〕 which are not cyclohexylphenol derivatives. ==See also==
* CP 55,940 * Cannabidiol * Cannabicyclohexanol
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「O-1871」の詳細全文を読む
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