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Omarigliptin : ウィキペディア英語版
Omarigliptin

Omarigliptin (MK-3102) is a potent, long-acting oral antidiabetic drug of the DPP-4 inhibitor class used for once-weekly treatment of type 2 diabetes and currently under development by Merck & Co. 〔(【引用サイトリンク】 title=Pharmacokinetics of Omarigliptin (Mk-3102), A Once-Weekly Dipeptidyl Peptidase-IV (DPP-4) Inhibitor, in Patients With Renal Impairment )〕 It inhibits DPP-4 to increase incretin levels (GLP-1 and GIP), which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying and decreases blood glucose levels.
==History==
MARIZEV (omarigliptin) 25 mg and 12.5 mg tablets were approved by Japanese Pharmaceuticals and Medical Devices Agency or PMDA on 28th Sept 2015. Japan was the first country to have approved omarigliptin.


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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