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Ophiorrhiza
''Ophiorrhiza'' is a genus of flowering plants in the coffee (Rubiaceae) family. Species of the genus contain camptothecin, an alkaloid used to make chemotherapeutic agents.〔Joseph, G. and J. P. Joseph. (Rediscovery of ''Ophiorrhiza caudata'' (Rubiaceae) from the Western Ghats of Kerala. ) ''Rheedia'' 19 45.〕〔Viraporn, V., et al. (2010). Correlation of camptothecin-producing ability and phylogenetic relationship in the genus ''Ophiorrhiza''. ''Planta Med''. in pub.〕 So many of Ophiorrhiza species are endemic to certain areas of western Ghats. Species include: *''Ophiorrhiza acuminata''〔Sirikantaramas, S., et al. (2008). (Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants. ) ''PNAS'' 105:18 6782.〕 *''Ophiorrhiza blumeana''〔Arbain, D, et al. (1998). (Unusual indole alkaloids from ''Ophiorrhiza blumeana'' Korth. ) ''J. Chem. Soc., Perkin Trans'' 1.〕 *''Ophiorrhiza bracteata''〔 *''Ophiorrhiza cantoniensis'' *''Ophiorrhiza carinata'' *''Ophiorrhiza caudata''〔 *''Ophiorrhiza dulongensis'' *''Ophiorrhiza filistipula'' *''Ophiorrhiza japonica'' *''Ophiorrhiza kuroiwai''〔Asano, T., et al. (2004). (Camptothecin production by ''in vitro'' cultures of ''Ophiorrhiza liukiuensis'' and ''O. kuroiwai''. ) ''Plant Biotechnology'' 21:4 275.〕 *''Ophiorrhiza liukiuensis''〔 *''Ophiorrhiza longiflora'' *''Ophiorrhiza lurida'' *''Ophiorrhiza major''〔 *''Ophiorrhiza michelloides''〔Chu, F., et al. (2006). (Taxonomic Status of ''Ophiorrhiza michelloides'' (Masam.) X. R. Lo (Rubiaceae) in Taiwan. ) ''Taiwania'' 51:2 143.〕 〔Nakamura, K., et al. (2006). Phylogenetic systematics of the monotypic genus ''Hayataella'' (Rubiaceae) endemic to Taiwan. ''Journal of Plant Research'' 119:657–661.〕 *''Ophiorrhiza mungos'' *''Ophiorrhiza nutans'' *''Ophiorrhiza prostrata''〔 *''Ophiorrhiza pumila''〔 〔Nakamura, K., et al. (2006). Homostyly and autogamy in ''Ophiorrhiza pumila'' (Rubiaceae) in the Ryukyu Archipelago. ''Journal of Japanese Botany'' 81:113–120.〕 *''Ophiorrhiza rosea'' *''Ophiorrhiza rugosa'' *''Ophiorrhiza succirubra'' ==References==
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