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Ortho-Vanillin : ウィキペディア英語版
Ortho-Vanillin

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''ortho''-Vanillin (''2-Hydroxy-3-methoxybenzaldehyde'') is an organic solid present in the extracts and essential oils of many plants.〔
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〕 Its functional groups include aldehyde, ether and phenol. ''ortho''-Vanillin, a compound of the formula C8H8O3, is distinctly different from its more prevalent isomer, vanillin. The "''ortho''-" prefix refers to the position of the compound’s hydroxyl moiety, which is found in the ''para''-position in vanillin.
''ortho''-Vanillin is a fibrous, light-yellow, crystalline solid. Unlike its better-known analogue, ''o''-vanillin does not have the characteristic and intense odor of vanilla. Present in a variety of food products, it is not specifically sought after, and is therefore a less-commonly produced and encountered food additive.
== History ==
''ortho''-Vanillin was first isolated, in 1876, by renowned German chemist Ferdinand Tiemann. By 1910, methods for its purification had been developed by Francis Noelting, who similarly demonstrated its versatility as a general synthetic precursor for a diverse array of compounds, such as the coumarins.〔Noelting, Francis A. M. o-Hydroxy-m-methoxybenzaldehyde (Orthovanillin). Annales de Chimie et de Physique (1910), 19, 476–550.〕
By 1920, the compound began to show use as a dye for hides.〔Gerngross, Otto. Dyeing hide with o-vanillin and o-protocatechualdehyde and the aldehyde tanning. Angewandte Chemie (1920), 33 (44), 136–138.〕

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