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Osteo-odonto-keratoprosthesis (OOKP) (also known as "tooth in eye" surgery) is a medical procedure to restore vision in the most severe cases of corneal and ocular surface patients. It includes removal of a tooth from the patient or a donor. After removal, a lamina of tissue cut from the tooth is drilled and the hole is fitted with optics. The lamina is grown in the patients' cheek for a period of months and then is implanted upon the eye. The procedure was pioneered by the Italian ophthalmic surgeon Professor Benedetto Strampelli in the early 1960s. Strampelli was a founder-member of the International Intra-Ocular Implant Club (IIIC) in 1966〔(National Dental Centre - 25 May 2005 TOOTH-IN-EYE (OOKP) SURGERY HELP 8 REGAIN SIGHT )〕 == Medical uses == An operation to graft the OOKP is undertaken in severe pemphigoid, chemical burns, Stevens–Johnson syndrome, trachoma, Lyell syndrome and multiple corneal graft failure. There is a significant risk of anatomical failure of lamina in the long term, estimated at about 19% in a small study, with the main risks being laminar resorption, particularly in allografts, and glaucoma. Another, bigger study comparing OOKP with the lesser known osteo-keratoprosthesis (OKP) in 145 and 82 patients and follow-up terms up to 10 years yielded following statistics: * 10-year anatomical survival: 66% for OOKP and 47% for OKP * 2-year functional survival: 63% for OOKP and 49% for OKP * 10-year functional survival: 38% for OOKP and 17% for OKP with functional survival defined as best corrected visual acuity above 0.05. Another long-term study of 181 patients puts the chances of retaining an intact OOKP after 18 years at 85%. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Osteo-odonto-keratoprosthesis」の詳細全文を読む スポンサード リンク
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