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・ Osteoblast
・ Osteoblast milk protein
・ Osteoblastoma
・ Osteobrama
・ Osteobrama alfredianus
・ Osteobrama bakeri
・ Osteobrama belangeri
・ Osteobrama bhimensis
・ Osteobrama cotio
・ Osteobrama cotio cotio
・ Osteobrama cotio cunma
・ Osteobrama cotio peninsularis
・ Osteobrama feae
・ Osteobrama neilli
・ Osteobrama vigorsii
Osteocalcin
・ Osteocephalus cabrerai
・ Osteocephalus deridens
・ Osteocephalus exophthalmus
・ Osteocephalus fuscifacies
・ Osteocephalus heyeri
・ Osteocephalus leoniae
・ Osteocephalus mutabor
・ Osteocephalus oophagus
・ Osteocephalus planiceps
・ Osteocephalus yasuni
・ Osteochilichthys
・ Osteochilichthys brevidorsalis
・ Osteochilus
・ Osteochilus brachynotopteroides


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Osteocalcin : ウィキペディア英語版
Osteocalcin

:''Not to be confused with Osteonectin or Osteopontin.''
Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. Because it has gla domains, its synthesis is vitamin K dependent. In humans, the osteocalcin is encoded by the ''BGLAP'' gene. Its receptor is GPRC6A.
== Function ==

Osteocalcin is secreted solely by osteoblasts and thought to play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building, by nature.〔 It is also implicated in bone mineralization and calcium ion homeostasis. Osteocalcin acts as a hormone in the body, causing beta cells in the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin.
Osteocalcin acts on Leydig cells of the testis to stimulate testosterone biosynthesis and therefore affect male fertility.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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