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Oxaprotiline
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Oxaprotiline : ウィキペディア英語版
Oxaprotiline

Oxaprotiline (C 49-802 BDA), also known as hydroxymaprotiline, is a norepinephrine reuptake inhibitor of the tetracyclic antidepressant family that is related to maprotiline. Though investigated as an antidepressant, it was never marketed.
==Chemistry==
Oxaprotiline is a racemic compound composed of two isomers, ''R''(−)- or levo- oxaprotiline (levoprotiline; CGP-12,103-A), and ''S''(+)- or dextro- oxaprotiline (dextroprotiline; CGP-12,104-A). Both enantiomers are active, with the levo- form acting merely as an antihistamine and the dextro- form having a more expansive pharmacology (see below), but with both unexpectedly still retaining antidepressant effects.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Oxaprotiline」の詳細全文を読む



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