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P450scc : ウィキペディア英語版
Cholesterol side-chain cleavage enzyme

Cholesterol side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an acronym for side-chain cleavage. P450scc is a mitochondrial enzyme that catalyzes conversion of cholesterol to pregnenolone. This is the first reaction in the process of steroidogenesis in all mammalian tissues that specialize in the production of various steroid hormones.
P450scc is a member of the cytochrome P450 superfamily of enzymes (family 11, subfamily A, polypeptide 1). The gene name is CYP11A1.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1583 )
== Nomenclature ==

The systematic name of this enzyme class is cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving). Other names include:
* C27-side-chain cleavage enzyme
* cholesterol 20-22-desmolase
* cholesterol C20-22 desmolase
* cholesterol desmolase
* cholesterol side-chain cleavage enzyme
* cholesterol side-chain-cleaving enzyme
* cytochrome P-450scc
* desmolase, steroid 20-22
* enzymes, cholesterol side-chain-cleaving
* steroid 20-22 desmolase
* steroid 20-22-lyase.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Cholesterol side-chain cleavage enzyme」の詳細全文を読む



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