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・ Pakhal Tirumal Reddy
・ Pakhala
・ Pakham District
・ Pakhangba
・ Pakhanjore
・ Pakhanna
・ Pakhanpur
・ Pak'nSave
・ Pak, Afghanistan
・ Pak-Arab Refinery
・ Pak-China Friendship Centre
・ Pak-Tong language
・ PAK1
・ PAK1IP1
・ PAK2
PAK3
・ PAK4
・ PAK6
・ PAK7
・ Paka
・ Paka (Peru)
・ Paka (river)
・ Paka (volcano)
・ Paka pri Predgradu
・ Paka pri Velenju
・ Paka, Dobrepolje
・ Paka, Malaysia
・ Paka, Mislinja
・ Paka, Požega-Slavonia County
・ Paka, Vitanje


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PAK3 : ウィキペディア英語版
PAK3

Serine/threonine-protein kinase PAK 3 is an enzyme that in humans is encoded by the ''PAK3'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5063 )
== Function ==

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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