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Words near each other
・ Pardo River
・ Pardo River (Amazonas)
・ Pardo River (Bahia)
・ Pardo River (Das Velhas River)
・ Pardo River (Mato Grosso do Sul)
・ Pardo River (Paranapanema River)
・ Pardo River (Ribeira River)
・ Parcé
・ Parcé-sur-Sarthe
・ Pard
・ Pard (legendary creature)
・ Pard Pearce
・ Pard Sar
・ PARD3
・ PARD3B
PARD6A
・ PARD6B
・ Parda
・ Parda Hai Parda
・ Parda Hai Parda (1992 film)
・ Pardachirus
・ Pardachirus marmoratus
・ Pardada Pardadi Educational Society
・ Pardailhan
・ Pardaillan
・ Pardaillan, Lot-et-Garonne
・ Pardal
・ Pardal Mallet
・ Pardalabad, Zahedan
・ Pardalabad-e Hesarooie


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PARD6A : ウィキペディア英語版
PARD6A

Partitioning defective 6 homolog alpha is a protein that in humans is encoded by the ''PARD6A'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50855 )
== Function ==

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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