翻訳と辞書 Words near each other ・ PDCD1LG2 ・ PDCD2 ・ PDCD4 ・ PDCD5 ・ PDCD6 ・ PDCD6IP ・ PDCD7 ・ PDCI ・ PDCP ・ PDCP College Basaith Benipatti ・ PDCurses ・ PDD (disambiguation) ・ PDD-62 ・ PDE ・ PDE surface ・ PDE1 ・ PDE10A ・ PDE11A ・ PDE1A ・ PDE1B ・ PDE1C ・ PDE2A ・ PDE3 inhibitor ・ PDE4A ・ PDE4B ・ PDE4C ・ PDE4D ・ PDE5 drug design ・ PDE5 inhibitor ・ PDE6A Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク PDE1 ： ウィキペディア英語版 PDE1 PDE1 (phosphodiesterase type 1) is a phosphodiesterase enzyme also known as calcium- and calmodulin-dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PDE1-PDE11). PDE1 has three subtypes, PDE1A, PDE1B and PDE1C which divide further into various isoforms. The various isoforms exhibit different affinities for cAMP and cGMP.〔〔 ==Discovery == The existence of the Ca2+-stimulated PDE1 was first demonstrated by Cheung (1970), Kakiuchi and Yamazaki (1970) as a result of their research on bovine brain and rat brain respectively. It has since been found to be widely distributed in various mammalian tissues as well as in other eukaryotes. It is now one of the most intensively studied member of the PDE superfamily of enzymes,〔 which today represents 11 gene families,〔 and the best characterized one as well.〔 Further researches in the field along with increased availability of monoclonal antibodies have shown that various PDE1 isozymes exist and have been identified and purified. It is now known that PDE1 exists as tissue specific isozymes.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「PDE1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.