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PF-4455242
PF-4455242 is a selective, short-acting antagonist of the κ-opioid receptor. Discovered by Pfizer in 2009, it was pursued in a phase I clinical trial for the treatment of bipolar disorder, and was also reportedly investigated as a treatment for depression and substance abuse. However, development was stopped in September 2010 due to toxicology findings in animals that had been exposed to the drug for three months.〔 ==See also==
* CERC-501 * ALKS-5461 * JDTic
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