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・ Pheidole epiphyta
・ Pheidole fervens
・ Pheidole fossimandibula
・ Pheidole gracilipes
・ Pheidole gymnoceras
・ Phazotron
・ Phaëton (Lully)
・ Pha̍k-fa-sṳ
・ Pha̍k-oa-chhi romanization
・ PHB
・ PHB (bicycle)
・ PHB2
・ PHBV
・ PHC
・ PHC Zebras
PHC1
・ PHC2
・ PHC3
・ PHCC
・ PHCCC
・ PHD
・ PhD confirmation
・ PhD Docbook renderer
・ PHD finger
・ PhD in management
・ PHD Mountain Software
・ PhD-MBA
・ PhDiA
・ PhDTree Project
・ PHE


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PHC1 : ウィキペディア英語版
PHC1

Polyhomeotic-like protein 1 is a protein that in humans is encoded by the ''PHC1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1911 )
== Function ==

This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.〔
Mutations in this gene have been associated to cases of primary microcephaly (doi: 10.1093/hmg/ddt072).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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